The lack of effectiveness of the Covid vaccines, which were developed for virus variants that have not been circulating for a long time, could still be expensive for those who have been vaccinated: the Belgian virologist and vaccine specialist Dr. Geert Vanden Bossche in a recent drafting.
the title: “The low virus neutralization capacity in populations heavily vaccinated against C-19 could soon result in a fulminant spread of Sars-CoV-2 supervariants, which are highly infectious and highly virulent in vaccinates, while at the same time being completely resistant to all existing and future spike-based ones C-19 vaccines are”
Vanden Bossches summarizes his urgent warning as follows:
I SERIOUSLY believe that a number of new highly virulent and highly infectious SARS-CoV-2 (SC-2) variants are now emerging rapidly and independently in highly vaccinated countries around the world and will soon be spreading at a rapid rate. I expect that the current pattern of recurrent infections and relatively mild illness in vaccinees will soon worsen and will be replaced by serious illness and death.
In essence, Vanden Bossche, who has been warning of the potential effects of mass vaccination campaigns for several months, notes that vaccinations with unsuitable and poorly effective vaccines have a negative impact on the immune system of vaccinated people: vaccinated people cannot protect themselves when they come into contact with SARS-CoV-2 variants rely more on their immune system, as the innate neutralizing IgM antibodies are very easily outperformed by vaccine-induced antibodies, which have a high affinity for SARS-CoV-2. The vaccine-induced antibodies therefore bind much more to the corresponding receptors of the virus and thus displace the body’s own antibodies, so to speak. However: These vaccine antibodies are not virus-neutralizing, but rather have an infection-strengthening effect.
On the other hand, those who are not vaccinated have an advantage thanks to the omicron variant: their innate immune system is trained by contact with the virus on SARS-CoV-2. In the absence of vaccination-induced, infection-enhancing antibodies, they are also better equipped to deal with more virulent variants.
While a natural pandemic naturally leads to herd immunity, a pandemic disrupted by mass vaccination campaigns that are unable to break the chain of virus transmission will eventually allow the virus to fully resist the immune response induced by the vaccine. As a result of increasing population-level immune pressure on viral infectivity (caused by vaccine anti-RBD antibodies), in a first step, the virus will escape potentially neutralizing antibodies and increase its infectivity (ADEI). This has now translated into the dominant circulation of Omicron, which is highly infectious and largely resistant to potentially neutralizing vaccine antibodies. As a result of the increased immune pressure that heavily vaccinated populations are now exerting on C-type lectin-mediated viral “trans-infectivity” (caused by non-neutralizing, “enhancing” anti-NTD antibodies), the virus will multiply into a likely to evolve the next step to also increase its virulence, thereby causing a dramatic increase in ADEDs and deaths in vaccinees. Because the mechanism of amplification of infection and disease is mediated through the binding of non-neutralizing antibodies directed to a conserved site on the spike protein, the occurrence of ADEI and ADED will be particularly pronounced in “heavily vaccinated – heavily boosted” populations, exposed to an SC-2 variant that is broadly resistant to vaccine antibodies that potentially inhibit viral infection (ie, virus-neutralizing antibodies).
In order to protect those who have been vaccinated, Vanden Bossche is now calling for large-scale antiviral prophylactic programs in countries with a high vaccination rate – otherwise, in his opinion, many people could die.
There have long been warnings about the danger of antibody-dependent amplification in Covid vaccines, but all calls went unheeded – or were branded as conspiracy theories. However, it is already a fact that the vaccines against Omikron do not show any convincingly proven effect. It can also be seen from data from different countries that that those who have been vaccinated are apparently more likely to fall ill than those who have not been vaccinated – and that despite the actually mild omicron variant, it can be severe (see for example here, here and here).
dr. Geert Vanden Bossche is not just anyone. Today he may be a thorn in the side of those on the vaccination agenda because his work is geared towards the well-being of people rather than the profits of the pharmaceutical industry. But in the past, his expertise in preparing for pandemics was still trusted: he even held a senior position at the Global Alliance for Vaccines and Immunization (GAVI) and was closely involved in various vaccine research and development.